On claiming the top spot for the second time after 2005, the Indian actress said: "I'm glad I got the crown back and will try and hold on to it this time.
"I think sexiness goes beyond looks and is a total package, from your personality to the way you carry yourself in your everyday life. I'm really grateful to all who voted for me because I work very hard," added the actress, who is looking forward to her next release Dhan Dhana Dhan Goal.
Commenting on Bipasha's international appeal, Hamant Verma, editor of Eastern Eye and the founder of its Sexiest Asian Women in the World List, said: "Bipasha is a living embodiment of sexual attractiveness. Her acting ability, beauty and charm are capable of arousing great interest in her from the world media."
Last year's winner, former Miss World and Bollywood actress Priyanka Chopra, bagged the third position this year while actress Madhuri Dixit was voted the runner-up.
The other Bollywood actresses who made it to the top 10 positions are Aishwarya Rai, voted as the fourth sexiest Asian woman and Shilpa Shetty, who came in sixth followed by Katrina Kaif, Kareena Kapoor and Lara Dutta. The public voted for those they thought were the sexiest Asian women from a list of 100 names published in the newspaper and on its website. The chairman of the judges' panel was Eastern Eye's show business editor Asjad Nazir.